The Bill & Melinda Gates Foundation is inviting proposals for the latest round of Grand Challenges Explorations. Grand Challenges Explorations fosters early-stage discovery research to expand the pipeline of ideas for solving our greatest global health and development challenges. Launched in 2008 with an initial $100 million commitment from the foundation, Grand Challenges Explorations grants have already been awarded to more than 1,200 researchers in more than 65 countries. Applicants can be at any experience level; in any discipline; and from any organization, including colleges and universities, government laboratories, research institutions, non-profit organizations, and for-profit companies. Initial grants will be US $100,000 each, and projects showing promise will have the opportunity to receive additional funding of up to US $1 million. The deadline for applications on the following four topics until May 3, 2017: Health Systems Strengthening: Ensuring Effective Health Supply Chains New Approaches for Improving Timeliness of Routine Immunizations in Low-Resource Settings Wearables and Technology for Maternal, Neonatal and Child Health Behavior Change Innovations for Integrated Diagnostics Systems Full descriptions of the new topics and application instructions in English, French, Korean, Portuguese, Chinese and Spanish will be available very soon. Check these two blogs: Innovation for an Interconnected Laboratory System and Improving Timeliness and Completeness of Routine Immunizations in Low-Resource Settings Will Save Lives. For details and application instructions, please visit the Grand Challenges website.